WebFeb 10, 2024 · The activity of released LDH was detected to evaluate cell death with the CytoTox96 LDH release kit (G1780, Promega) following the manufacturer’s instructions. The LDH activity in the supernatants was expressed as a percentage of total LDH in the cell lysate. Data Analysis The Student’s t -test was used for two-group comparisons. WebMay 20, 2010 · CytoTox96 LDH-release kit was from Promega. Mouse Macrophage Cell Culture J2 retrovirus (carrying v-myc and v-raf oncogenes)-immortalized macrophage cell lines were used in all experiments. Immortalized bone marrow-derived macrophage cell lines deficient in NLRC4 (NLRC4-KO), NLRP3 (NLRP3-KO) or ASC (ASC-KO) were obtained …
Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes …
WebPromega ldh cytotox 96 non radioactive cytotoxicity assay kit Ldh Cytotox 96 Non Radioactive Cytotoxicity Assay Kit, supplied by Promega, used in various techniques. … WebSep 16, 1997 · Following a 2-h incubation at 37°C (5% CO 2), gentamicin was added to a final concentration of 50 μg/ml. Supernatants of the infected macrophages were sampled and assayed for lactate dehydrogenase (LDH) using the cytotox 96 kit (Promega) according to the manufacturer’s instructions. The percent cell death was calculated as 100 × ... cycl root adverb
CytoTox 96® Non-Radioactive Cytotoxicity Assay Protocol
WebOct 10, 2005 · The CytoTox 96 Non-Radioactive Cytotoxicity Assay from Promega is an easy-to-use, 2 step, colorimetric kit that provides a non-radioactive method for measuring this LDH release in the culture media. The kit comes with a substrate mix that is stored as a lypholized powder and provided in 4 vials for easy reconstitution and use. Web% Cytotoxicity = 100 × (Experimental LDH Release – Medium Background) / (Maximum LDH Release Control – Medium Background) I treat my cells (human pancreatic ductal cell line) with potentially... WebMar 6, 2024 · A detailed mechanistic assessment of cytotoxicity is essential for design and construction of more effective polycations for nucleic acid delivery. A single toxicity assay cannot stand alone in determining the type and extent of damage or cell death mechanism. In this chapter we describe a lactate dehydrogenase (LDH) assay for high-throughput ... cyclr systems ltd